Liquid Carrier for Oral Delivery of a Pharmacologically Active Agent
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United States of America Patent
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Issued Date -
Feb 13, 2014
app pub date -
Apr 20, 2012
filing date -
Apr 18, 2011
priority date (Note) -
Abandoned
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Abstract
A fluid carrier comprises first and second substantially immiscible liquids. The first liquid is an open-chain silicone oil of the formula [(CH3)3Si—O]—[(CH2)2Si—O]n—[Si(CH3)3]. The second liquid is a polar lipid material. The first and second liquids are capable of forming an unstable dispersion. The unstable dispersion can be stabilized by adding a powderous solid insoluble in the liquids. The powderous solid is selected from pharmacologically active agent, pharmaceutical excipient, and their mixtures. The stabilized dispersion is of a creamy or ointment-like or mouldable form, and can be filled into capsules or moulded into tablets so as to be fit for peroral administration.
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