BIOREACTOR WITH MECHANICAL AND ELECTRICAL STIMULATION MEANS

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United States of America Patent

APP PUB NO 20140038258A1
SERIAL NO

14005908

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed herein is a bioreactor for creating and/or conditioning biological tissues, in particular cardiovascular patches. This bioreactor supports additionally cellular differentiation under controlled conditions. The bioreactor comprises a housing having a first section (20) for holding a nutrition solution and/or a cell suspension (24), means (28) for holding a scaffold (34), said means being disposed or disposable inside said bioreactor housing such that said scaffold (34) held therein is exposed to said nutrition solution and/or cell suspension (24) when contained in said first section (20), mechanical stimulation means (54, 68, 86) for applying mechanical stress and/or strain to said scaffold (34) and/or tissue formed thereon when held by said scaffold holding means (28) in said bioreactor housing, and electrical stimulation means (38, 92) for applying an electrical stimulation to said scaffold (34) and/or tissue formed thereon when held by said scaffold holding means (28) in said bioreactor housing.

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Patent Owner(s)

Patent OwnerAddress
LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHENGESCHWISTER-SCHOLL-PLATZ 1 MUNICH 80539

International Classification(s)

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  • 2012 Application Filing Year
  • C12M Class
  • 668 Applications Filed
  • 452 Patents Issued To-Date
  • 67.67 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201220132014201520162017201820192020202120220255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Akra, Bassil Olching, DE 4 11
Koenig, Fabian Hugo Kiefersfelden, DE 1 4

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Patent Citation Ranking

  • 4 Citation Count
  • C12M Class
  • 11.24 % this patent is cited more than
  • 11 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges2813236189104421501 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 90100 +0102030405060708090100110120130140

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