Immunoglobulin 2
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United States of America Patent
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app pub date -
Jul 30, 2013
filing date -
Apr 24, 2001
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Abandoned
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Abstract
The present invention relates to a method for the generation of single chain immunoglobulins in a mammal. In particular, the present invention relates to a method for the generation of single chain camelid VHH antibodies in a mammal which undergo the process of class-switching and affinity maturation found within antibody producing B cells. Single chain antibodies generated using the method of the present invention and the uses thereof are also described.
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