LOSS OF 5-HYDROXYMETHYLCYTOSINE AS A BIOMARKER FOR CANCER
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United States of America Patent
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Issued Date -
Jan 30, 2014
app pub date -
Jan 22, 2013
filing date -
Jan 20, 2012
priority date (Note) -
Abandoned
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Abstract
Methods for detecting or diagnosing cancer in a subject are provided herein. Such methods may include, but are not limited to, measuring a test level of 5hmC in a biological sample from the subject; and determining that the subject has a malignant cancer when the test level of 5hmC is lower than that of a control level of 5hmC. Such methods may further include a step of measuring a test level of Ki67 in the biological sample and determining that the subject has a malignant cancer when the test level of Ki67 is higher than that of a control level of Ki67.
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