Small RNA-dependent translational regulatory system in cell or artificial cell model
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
Jun 16, 2015
Grant Date -
Jan 30, 2014
app pub date -
Sep 9, 2013
filing date -
Nov 22, 2007
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
An object of the present invention is to construct an mRNA which specifically responds to a short RNA sequence and can activate, repress, and regulate the translation of the desired gene, and to construct an artificial cell model system using a liposome comprising the mRNA and a cell-free translational system encapsulated therein. The present invention provides: an mRNA comprising a target RNA-binding site located immediately 5′ to the ribosome-binding site, and a nucleotide sequence located 5′ to the target RNA-binding site, the nucleotide sequence being complementary to the ribosome-binding site; an mRNA comprising a small RNA-binding site located 3′ to the start codon, and a nucleotide sequence located 3′ to the small RNA-binding site, the nucleotide sequence encoding a protein; and a liposome comprising any of these mRNAs encapsulated therein.
First Claim
Other Claims data not available
Family
International Classification(s)
- 2013 Application Filing Year
- C07H Class
- 1086 Applications Filed
- 1021 Patents Issued To-Date
- 94.02 % Issued To-Date
Cited Art Landscape
Patent Citation Ranking
- 1 Citation Count
- C07H Class
- 46.28 % this patent is cited more than
- 10 Age
Maintenance Fees
| Fee | Large entity fee | small entity fee | micro entity fee | due date |
|---|---|---|---|---|
| 11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Dec 16, 2026 |
