MODIFIED SOLUBLE FGF RECEPTOR FC FUSIONS METHOD
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Jun 28, 2013
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Nov 28, 2006
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Abstract
The invention relates to modified soluble FGF receptor Fc fusions comprising a fusion of a soluble fragment or domain of the FGF receptor part (targeting or binding moiety) with an Fc region of an immunoglobulin part (effector function moiety), having improved biological activity including ADCC/CDC activities, compositions containing them, and method of producing such modified soluble FGF receptor Fc fusion molecules.
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