MODULATORS FOR TRPA1 FOR THE TREATMENT OF ROSACEA
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United States of America Patent
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Issued Date -
Jan 23, 2014
app pub date -
Dec 19, 2011
filing date -
Dec 22, 2010
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Abandoned
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Abstract
An in vitro method of screening candidate compounds for the preventive or curative treatment of rosacea is described. The method can include determining the capacity of a compound to modulate the expression or activity of the Transient Receptor Potential (TRP) cation channel, subfamily A, member 1(TRPA1), as well as the use of modulators of the expression or activity of this transcription factor for the treatment of rosacea. The method can also include in vitro diagnosis or prognosis of this pathology.
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