METHODS AND COMPOSITIONS FOR PRESERVING RETINAL GANGLION CELLS
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United States of America Patent
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Issued Date -
Jan 23, 2014
app pub date -
Oct 21, 2011
filing date -
Nov 1, 2010
priority date (Note) -
Abandoned
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Abstract
Provided are methods and compositions for maintaining the viability of retinal ganglion cells in a subject with an ocular disorder including, for example, glaucoma and optic nerve injury. The viability of the retinal ganglion cells can be preserved by administering a necrosis inhibitor either alone or in combination with an apoptosis inhibitor to a subject having an eye with the ocular condition. The compositions, when administered, maintain the viability of the cells and/or promote axon regeneration, thereby minimizing the loss of vision or visual function associated with the ocular disorder.
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