PHOTO-UNCAGING-ASSISTED EVALUATION OF LARGE-SCALE SYNAPTIC REORGANIZATION OF BRAIN CIRCUITS
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United States of America Patent
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Issued Date -
Jan 23, 2014
app pub date -
Sep 23, 2013
filing date -
May 2, 2012
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Abstract
Photouncaging-assisted evaluation of large-scale synaptic reorganization of brain circuits and methods in use thereof. The current invention utilizes laser-scanning photostimulation in large-scale and with higher accuracy to detect synaptic reorganization in neurological disorders, such as Alzheimer's disease, Parkinson's disease and epilepsy. Using the invention's methodology, disease and non-disease conditions can be determined, and treatments can be personalized and administered more efficiently.
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