REVERSIBLY WATER-SOLUBLE NANOCRYSTALS
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United States of America Patent
Stats
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N/A
Issued Date -
Jan 2, 2014
app pub date -
Jan 20, 2012
filing date -
Jan 20, 2012
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
A general, facile, and reversible nanocrystal (NCs) phase transfer protocol via ligand exchange using nucleotides and/or nucleosides is provided to generate reversibly water-soluble nanocrystals. This phase transfer strategy can be employed on a wide variety of chemically synthesized nanostructured materials including semiconductors, metal oxides and noble metals with different sizes and shapes. The nucleotide/nucleoside-capped nanocrystals can disperse homogeneously in aqueous or alcohol media retaining, for example, high photoluminescence quantum yields. The disclosed water-soluble nanocrystals have excellent colloidal and photoluminescent stability independent on the pH and ionic strength, minimal hydrodynamic size, and are stable in cells and suitable for in vitro cell labeling, cell tracking, and other bioimaging applications.
First Claim
all claims..Other Claims data not available
Family
Country | kind | publication No. | Filing Date | Type | Sub-Type |
---|---|---|---|---|---|
WO | A1 | WO2013107041 | Jan 20, 2012 | Patent | Application |
Type : Patent Sub-Type : Application | |||||
INTERNATIONAL APPLICATION PUBLISHED WITH INTERNATIONAL SEARCH REPORT | REVERSIBLY WATER-SOLUBLE NANOCRYSTALS CAPPED BY NUCLEOTIDES AND/OR NUCLEOSIDES | Jul 25, 2013 |
- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | |
---|---|---|
EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY | 200237 NO 130 MEILONG ROAD SHANGHAI XUHUI DISTRICT SHANGHAI CITY SHANGHAI CITY 200237 |
International Classification(s)

- 2012 Application Filing Year
- G01N Class
- 8064 Applications Filed
- 6361 Patents Issued To-Date
- 78.89 % Issued To-Date
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
---|---|---|---|
Liu, Lu | Shanghai, CN | 332 | 1323 |
# of filed Patents : 332 Total Citations : 1323 | |||
Zhong, Xinhua | Shanghai, CN | 5 | 132 |
# of filed Patents : 5 Total Citations : 132 |
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Patent Citation Ranking
- 1 Citation Count
- G01N Class
- 13.80 % this patent is cited more than
- 11 Age
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Maintenance Fees
Fee | Large entity fee | small entity fee | micro entity fee | due date |
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11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Jul 2, 2025 |
Fee | Large entity fee | small entity fee | micro entity fee |
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Surcharge - 11.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |
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