METHOD FOR SYNTHESIZING PIRFENIDONE

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United States of America Patent

APP PUB NO 20130345430A1
SERIAL NO

13947643

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Abstract

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A process for synthesizing pirfenidone from bromobenzene having less than about 0.15% by weight dibromobenze is disclosed. Also disclosed are processes of synthesizing pirfenidone without using ethyl acetate or n-butanol, and pirfenidone having controlled levels of ethyl acetate, n-butanol, di(5-methyl-2-pyridinone)benzenes, and other impurities having specified retention times. Also disclosed are formulated dosage forms including the disclosed pirfenidone.

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Patent Owner(s)

Patent OwnerAddress
INTERMUNE INCBRISBANE CA 94005-1021

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cyr, Michael League City, US 9 116
Pyles, Sabine M Houston, US 6 21
Radhakrishnan, Ramachandran Fremont, US 46 1795

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