Use of ID4 for Diagnosis and Treatment of Cancer
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United States of America Patent
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Issued Date -
Dec 26, 2013
app pub date -
Aug 7, 2009
filing date -
Feb 1, 2005
priority date (Note) -
Abandoned
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Abstract
Methods for diagnosis and treatment of cancer using ID4 are disclosed. Specifically, epigenetic inactivation of ID4 in colorectal carcinomas and breast correlates with poor differentiation and unfavorable prognosis. Further, aberrant hypermethylation of ID4 gene promoter region increases risk of metastasis in colorectal and breast cancer.
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