COMPOSITIONS AND METHODS FOR TOPICAL NITRIC OXIDE GENERATION
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United States of America Patent
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Issued Date -
Dec 12, 2013
app pub date -
Nov 29, 2012
filing date -
Dec 5, 2011
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Abandoned
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Abstract
A simple, biocompatible two-component system and procedure for generating nitric oxide (NO) is described. One component comprises sodium nitrite or other nitrite source, and the other component comprises a reductant, an acid and a base although in certain embodiments the reductant and acid functions are provided by the same component. When these two components are mixed directly at a local site of administration or immediately prior to application and the mixture generates nitric oxide (NO) for topical application. The activated system is therapeutic for treatment of multiple conditions, including promotion of healing, disinfection, promotion of hair growth, and treatment of male and female sexual dysfunction.
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