ATROPISOMERS OF P13K-INHIBITING COMPOUNDS
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United States of America Patent
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Issued Date -
Dec 5, 2013
app pub date -
Sep 23, 2011
filing date -
Sep 24, 2010
priority date (Note) -
Abandoned
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Abstract
The invention provides compounds, compositions and methods to treat certain inflammatory conditions or cancers by administering a compound that inhibits PI3K isoforms, wherein the compounds are optically active atropisomers. It provides optically active stereoisomers of a class of pyrazole-containing compounds, which are useful for these methods, and provides methods to obtain these compounds as well as pharmaceutical compositions containing these compounds.
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