Use of Artemisine Derivatives and Pharmaceutical Salts Thereof
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United States of America Patent
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Issued Date -
Nov 28, 2013
app pub date -
Jan 16, 2012
filing date -
Jan 31, 2011
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Abstract
The invention demonstrates the application of an artemisinin derivative and its pharmaceutical salt. The artemisinin derivatives diarteether amine and its pharmaceutical salt inhibit the proliferation of leukemic cells, block the cell cycle of leukemic cells and induce the apoptosis of leukemic cells. Artemisinin derivatives of the present invention and its pharmaceutical salt can be used for the preparation of anti-leukemia medicines, especially for treatment of acute leukemia and, what's more, for the treatment of acute myeloid leukemia.
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