Composition for Enhancing Cellular Uptake of Carrier Particles and Method for the Same
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United States of America Patent
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Nov 28, 2013
app pub date -
May 21, 2013
filing date -
May 22, 2012
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Abstract
A composition for enhancing cellular uptake of carrier particles comprises a delivery system for a drug or biochemical molecule; and a polyphenolic compound, wherein the polyphenolic compound is added to the drug or biochemical molecule delivery system to enhance cellular uptake of drug or biochemical molecules carried by the delivery system. A method for the same is also disclosed, wherein a polyphenolic compound or its derivative is mixed with an existing delivery system for drug or biochemical molecule, and the mixture is used to deliver drug or biochemical molecules into cells or an organism. The method is easy to operate and does not require further chemical reaction in process of the existing delivery system. The delivery system may include a magnetic carrier that can be guided to a specified region by an external magnetic field, consequently increased the amount of the drug or biochemical molecules acting on target cells.
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