Method for Modifying a Property of a Protein

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United States of America Patent

SERIAL NO

13939291

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Abstract

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A method for improving the thermostability of a protein includes introducing, into the protein, two or more amino acid substitutions selected from the group consisting of: (i) substitution of an arginine residue for a lysine residue, (ii) substitution of a threonine residue for a serine residue, and (iii) substitution of an alanine residue for a serine residue.

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Patent Owner(s)

Patent OwnerAddress
AJINOMOTO CO INCCHUO-KU TOKYO 104-8315
NATIONAL INSTITUTE OF TECHNOLOGY AND EVALUATIONTOKYO 151-0066

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gojobori, Takashi Mishima-shi, JP 7 94
Hino, Yumi Yokohama-shi, JP 5 49
Hori, Eiichi Tokyo, JP 2 25
Ikeo, Kazuho Mishima-shi, JP 6 93
Kawarabayashi, Yutaka Kisarazu-shi, JP 3 25
Kimura, Eiichiro Tokyo, JP 25 172
Nakamura, Yoji Mishima-shi, JP 6 35
Nishio, Yosuke Kawasaki-shi, JP 13 43
Usuda, Yoshihiro Kawasaki-shi, JP 63 1078
Yamazaki, Jun Tokyo, JP 67 476

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