NANOPROBE COMPRISING GOLD COLLOID NANOPARTICLES FOR MULTIMODALITY OPTICAL IMAGING OF CANCER AND TARGETED DRUG DELIVERY FOR CANCER

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United States of America Patent

APP PUB NO 20130315834A1
SERIAL NO

13825810

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention is directed to a nanoparticle loaded with a light sensitive molecule and a method of preparing the nanoparticle, wherein the nanoparticle is a colloidal gold nanoparticle and the light sensitive molecule is non-covalently adsorbed to the surface of the nanoparticle. The present invention is also directed to a nanoprobe comprising the nanoparticle and further comprising a targeting moiety covalently coupled to the surface of the nanoparticle. Additionally, the present invention is directed to an imaging method comprising administering the nanoprobe to a subject and collecting imaging data of the subject or part of the subject with optical multimodality imaging. A method of treating cancer in a subject comprising administering the nanoprobe and performing photodynamic therapy on the subject is further disclosed.

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Patent Owner(s)

Patent OwnerAddress
AGENCY FOR SCIENCE TECHNOLOGY AND RESEARCH2 FUSIONOPOLIS WAY #08-01 INNOVIS SINGAPORE 13863
SINGAPORE HEALTH SERVICES PTE LTD31 THIRD HOSPITAL AVENUE #03-03 BOWYER BLOCK C SINGAPORE 168753

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Olivo, Malini Singapore, SG 31 41
Praveen, Nagamani Singapore, SG 2 17
Thoniyot, Praveen Singapore, SG 11 32

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