Growth-regulated viral vector containing the aurora kinase promoter
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United States of America Patent
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Aug 11, 2020
Grant Date -
Nov 21, 2013
app pub date -
Sep 29, 2011
filing date -
Sep 30, 2010
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Abstract
Disclosed is a vector, preferably a viral vector, containing a treatment factor and/or a nucleic acid encoding a cytotoxic factor under control of an Aurora kinase promoter. Also disclosed is a virus vector in which the promoter of a nucleic acid encoding a factor necessary to the replication or assembly of at least one virus is substituted by the Aurora kinase promoter. Also disclosed are a disease treatment agent, in particular a cancer treatment agent, which contains the aforementioned vector, and a clinical diagnostic agent, in particular a cancer diagnostic agent, which contains the vector containing the Aurora kinase promoter.
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