Cylodextrin Complexation Methods for Formulating Peptide Proteasome Inhibitors

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United States of America Patent

APP PUB NO 20130303465A1
SERIAL NO

13614599

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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This disclosure provides methods for formulating compositions comprising one or more peptide proteasome inhibitors and a cyclodextrin, particularly a substituted cyclodextrin. Such methods substantially increase the solubility and stability of these proteasome inhibitors and facilitate both their manufacture and administration.

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Patent Owner(s)

Patent OwnerAddress
ONYX THERAPEUTICS INC2100 POWELL STREET C/O ONYX PHARMAECUTICALS INC EMERYVILLE CA 94608

International Classification(s)

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  • 2012 Application Filing Year
  • A61K Class
  • 11964 Applications Filed
  • 9694 Patents Issued To-Date
  • 81.03 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201220132014201520162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dalziel, Sean San Francisco, US 20 125
Jumaa, Mouhannad Foster City, US 12 75
Lewis, Evan Pacifica, US 10 70
Shwonek, Peter San Francisco, US 3 16

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Patent Citation Ranking

  • 4 Citation Count
  • A61K Class
  • 14.18 % this patent is cited more than
  • 12 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges93340159383591527830328862201 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +025050075010001250150017502000225025002750300032503500375040004250

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