Methods and Devices For Treating Intervertebral Disc Disease
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United States of America Patent
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Issued Date -
Nov 7, 2013
app pub date -
Mar 15, 2013
filing date -
May 7, 2012
priority date (Note) -
Abandoned
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Abstract
Provided are methods for treating intervertebral disc degeneration, promoting tissue regeneration in the intervertebral disc, promoting homeostasis of the intervertebral disc, preventing intervertebral disc degeneration, and reducing inflammation of the intervertebral disc in a subject in need thereof comprising administering a myeloid differentiation primary response (88) (MyD88) antagonist to the subject. Also provided is a device, biomaterial or putty for implantation in or near the spine, wherein the device, biomaterial or putty is coated or infused with a myeloid differentiation primary response gene (88) (MyD88) antagonist.
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