PYRAZOLOQUINOLINE DERIVATIVES

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United States of America Patent

APP PUB NO 20130296352A1
SERIAL NO

13914898

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A compound and/or pharmacologically acceptable salt thereof represented by the formula (I) has PDE9 inhibitory action, so that the intracerebral cGMP concentration is anticipated to be elevated. The PDE9 inhibitory action and the increase in cGMP lead to the improvement of learning and memory behaviors, and the compound (I) has applicability as a therapeutic agent for cognitive dysfunctions in Alzheimer's disease.

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Patent Owner(s)

Patent OwnerAddress
EISAI R&D MANAGEMENT CO LTDTOKYO JAPAN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hagiwara, Koji Tsukuba, JP 25 194
Ishihara, Yuki Tsukuba, JP 11 51
Norimine, Yoshihiko Tsukuba, JP 20 470
Sato, Nobuaki Tsukuba, JP 75 1494
Suzuki, Yuichi Tsukuba, JP 178 2033
Takeda, Kunitoshi Tsukuba, JP 13 406

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