TARGETED AND LIGHT-ACTIVATED CYTOSOLIC DRUG DELIVERY
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United States of America Patent
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Issued Date -
Oct 31, 2013
app pub date -
Apr 22, 2011
filing date -
Apr 23, 2010
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Abandoned
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Abstract
The present invention provides methods and compositions for highly precise spatial and temporal control over cytosolic delivery of compounds, in particular, those compounds that would otherwise be cell-impermeable. Among other things, the present invention provides a composition for targeted drug delivery comprising a nanoparticle, a targeting moiety specific for a cell type of interest, a light-activated drug delivery system, wherein the nanoparticles are associated with the targeting moiety and the light-activated drug delivery system.
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