Reversible crosslinked polymers
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United States of America Patent
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Jul 19, 2022
Grant Date -
Oct 31, 2013
app pub date -
Apr 29, 2013
filing date -
Apr 27, 2012
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Abstract
A reversibly crosslinked polymer and methods for producing and using the obtained polymer are disclosed. In particular, reversibly crosslinked polymers of the invention comprise polyesters formed by the reaction of mercaptosuccinic acid and a diol to form a monomeric unit that includes thiol groups as crosslinking moieties. Oxidation of the thiol groups affords crosslinked polymer comprising a disulfide linkage that, upon reduction of the disulfide linkage, provides a non-crosslinked polymer. In some embodiments, polymers of the invention are degradable and are biocompatible.
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