NOVEL COMPOSITIONS AND USES OF ANTI-HYPERTENSION AGENTS FOR CANCER THERAPY

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United States of America Patent

APP PUB NO 20130287688A1
SERIAL NO

13834094

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Methods and compositions for improving the delivery and/or efficacy of a therapy (e.g., a cancer therapy) are disclosed. In one embodiment, methods and compositions for treating or preventing a cancer (e.g., a solid tumor such as a desmoplastic tumor) by administering to a subject an anti-hypertensive agent, as a single agent or in combination with a microenvironment modulator and/or a therapy, e.g., a cancer therapy (for example, a therapeutic agent or therapy, including immunotherapy (e.g., antibodies, vaccine, cell-based), nanotherapeutics, radiation therapy, photodynamic therapy, low molecular weight chemotherapeutics, molecularly targeted therapeutics and/or oxygen radical) are disclosed.

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Patent Owner(s)

Patent OwnerAddress
MASSACHUSETTS INSTITUTE OF TECHNOLOGY77 MASSACHUSETTS AVENUE CAMBRIDGE MA 02139
THE GENERAL HOSPITAL CORPORATION D/B/A MASSACHUSETTS GENERAL HOSPITAL55 FRUIT STREET BOSTON MA 02114

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Boucher, Yves Belmont, US 20 339
Chauhan, Vikash Pal Singh Cambridge, US 3 31
Crane, Alan L Newton, US 1 28
Diop-Frimpong, Benjamin Boston, US 1 28
Jain, Rakesh Kumar Wellesley, US 7 38
Krane, Stephen Cambridge, US 1 28
Langer, Robert Newton, US 306 7077

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