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• 15 United States
• 10 France
• 8 Japan
• 7 China
• 5 Korea
• 2 Other

Patent Owner(s)

Patent Owner	Address
SAMYANG BIOPHARMACEUTICALS CORPORATION	31 JONG-RO 33-GIL JONGNO-GU SEOUL 03129

International Classification(s)

• A61K:PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOS....

• 2011 Application Filing Year
• A61K Class
• 10915 Applications Filed
• 8360 Patents Issued To-Date
• 76.60 % Issued To-Date

Inventor(s)

Inventor Name	Address	# of filed Patents	Total Citations
Cho, Eun-Ah	Daejeon, KR	5	7
# of filed Patents : 5 Total Citations : 7
In, Chang-Hoon	Cheongju-si, KR	2	0
# of filed Patents : 2 Total Citations : 0
Kim, Sang-Hee	Daejeon, KR	41	903
# of filed Patents : 41 Total Citations : 903
Kim, Sun-Ok	Daejeon, KR	8	75
# of filed Patents : 8 Total Citations : 75

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• 0 Citation Count
• A61K Class

• 0 % this patent is cited more than
• 12 Age

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Full Text

US Patent Application No: 2013/0281,513

siRNA FOR INHIBITION OF Hif1alpha EXPRESSION AND ANTICANCER COMPOSITION CONTAINING THE SAME

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Abstract

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Disclosed are small interfering RNA (siRNA) that complementarily binds to a base sequence of Hif1α mRNA transcript, thereby inhibiting expression of Hif1α without inducing immune responses, and a use of the siRNA for prevention and/or treatment of cancer. Since Hif1α is commonly overexpressed in almost all cancer cells, the siRNA that complementarily binds to Hif1α-encoding mRNA may inhibit expression of Hif1α through RNA-mediated interference (RNAi), thereby inhibiting proliferation and metastasis of cancer cells, and thus, the siRNA may be useful as an anticancer agent.

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Description

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