siRNA Therapy for Transthyretin (TTR) Related Ocular Amyloidosis

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United States of America Patent

SERIAL NO

13636594

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Abstract

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The invention relates to a method of treating ocular amyloidosis by reducing TTR expression in a subject by administering a double-stranded ribonucleic acid (dsRNA) that targets a TTR gene to the retinal pigment epithelium of the subject.

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Patent Owner(s)

Patent OwnerAddress
ALNYLAM PHARMACEUTICALS INC675 WEST KENDALL STREET HENRI A TERMEER SQUARE CAMBRIDGE MA 02142-1110

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Alvarez, Rene Boxborough, US 25 259
Ando, Yukio Kumomoto, JP 36 285
Jono, Hirofumi Kumomoto, JP 11 69
Sah, Dinah Wen-Yee Boston, US 85 907

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