Manipulation of HSP70 and IRE1Alpha Protein Interactions
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United States of America Patent
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Issued Date -
Oct 24, 2013
app pub date -
Jun 8, 2011
filing date -
Jun 8, 2010
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Abandoned
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Abstract
The present invention relates to methods that manipulate the level of interaction between the proteins Hsp70 and IRE1α. In particular, the invention relates to methods of manipulating this interaction in order to increase protein yield, and to methods of manipulating this interaction in order to treat diseases associated with abnormal apoptotic activity, including cancer and autoimmune diseases.
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