SUB-2 MICRON CHIRAL STATIONARY PHASE SEPARATION AGENT
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Jan 31, 2013
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Apr 20, 2012
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Abstract
The present invention relates to a porous sub-2 chiral stationary phase agent that provides stability and increased productivity for chiral separation using HPLC and UHPLC methods. It was surprisingly discovered that highly stable and backpressure resistant coated and at least partially covalently bonded chiral stationary phase agents having an average particle diameter less than 2 microns can be obtained by maintaining a pore ratio of from 0.0042 to about 0.010.
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