PHARMACEUTICAL COMPOSITIONS TO TREAT FIBROSIS
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United States of America Patent
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Issued Date -
Oct 17, 2013
app pub date -
Apr 6, 2011
filing date -
Apr 8, 2010
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Abstract
The present invention provides methods for the prevention, treatment and/or amelioration of fibrosis or fibrotic conditions. The present invention further provides small molecule inhibitors of Wnt- and TGF-p-mediated β-catenin signaling to prevent, treat and/or ameliorate fibrosis or fibrotic conditions. Kits comprising small molecule inhibitors of Wnt- and TGF-p-mediated β-catenin signaling and methods of identifying small molecule inhibitors of Wnt- and TGF-p-mediated β-catenin signaling are also provided.
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