FREEZING MEDIUM COMPOSITION FOR CRYOPRESERVING AMNIOTIC FLUID-DERIVED STEM CELLS AND A METHOD FOR CRYOPRESERVING THE SAME

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United States of America Patent

APP PUB NO 20130267008A1
SERIAL NO

13578972

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Abstract

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Provided are to a freezing medium composition for cryopreserving amniotic fluid-derived stem cells, which has A lower concentration of Me2SO and eliminates fetal bovine serum and at the same time does not induce cryoinjury to fluid-derived stem cells and makes it possible to cryopreserve fluid-derived stem cells for a prolonged time using trehalose, sucrose and catalase, and a method for cryopreserving the same. According to the present invention, AFSCs can be cryopreserved with 1/4 the standard Me2SO concentration with the addition of disaccharides, antioxidants and caspase inhibitors. As a result, the use of Me2SO at low concentrations in cell freezing solutions may support the development of clinical trials of AFSCs.

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Patent Owner(s)

Patent OwnerAddress
KYUNGPOOK NATIONAL UNIVERSITY HOSPITAL130 DONGDEOK-RO JUNG-GU DAEGU 41944 41944

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Shon, Yun-Hee Daegu, KR 1 3
Suh, Jang-Soo Daegu, KR 1 3
Yoo, James J Winston-Salem, US 58 1100

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