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United States of America Patent
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Issued Date -
Oct 10, 2013
app pub date -
Mar 22, 2013
filing date -
Apr 5, 2012
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Abstract
A separator fractionates a dispersion of cells including cells having phagocytic activity corresponding to a size of the cells to obtain a dispersion in which the content of the cells having phagocytic activity is higher than that of the dispersion, and includes a filter, at least part of the filter having a hydrophilic surface as a result of being covered with at least one of a self-assembled monolayer that includes an alkanethiol having a nonionic hydrophilic group that is formed on a gold thin film via a sulfur-gold bond, and a homopolymer or a copolymer of an ester of (meth)acrylic acid and at least some of hydrophilic groups of phospholipids that form a biomembrane. The separator is thus configured so that clogging of the filter is suppressed, and the separation efficiency is improved.
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