ASSAY FOR A TYPE II COLLAGEN BIOMARKER
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United States of America Patent
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Issued Date -
Oct 3, 2013
app pub date -
Sep 16, 2011
filing date -
Sep 24, 2010
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Abandoned
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Abstract
An assay for Type II collagen fragments in serum, plasma, or synovial fluid obtains a quantitative measure of the concentration of all protein fragments in a serum, plasma, or synovial fluid sample that are reactive with an antibody, or immunoreactive antibody fragment, having specific reactivity with a C-terminal epitope present in the amino acid sequence GPPGRDGAAG and lacking specific reactivity with an amino acid sequence comprising the amino acid sequence GPPGRDGAAGV, which may be Mab NB44-3C1 as produced by the cell line deposited in HPA Culture Collection Logistics Office with Accession Number 10091402.
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