COPY NUMBER VARIATION DETERMINATION, METHODS AND SYSTEMS
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United States of America Patent
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Issued Date -
Oct 3, 2013
app pub date -
May 24, 2013
filing date -
Sep 7, 2007
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Abandoned
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Abstract
The present invention methods and systems for determining copy number variation of a target polynucleotide in a genome of a subject including amplification based techniques. Methods can include pre-amplification of the sample followed by distribution of sample and a plurality of reaction volumes, quantitative detection of a target polynucleotide and a reference polynucleotide, and analysis so as to determine the relative copy number of the target polynucleotide sequence in the genome of the subject.
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