Prediction of and Monitoring Cancer Therapy Response Based on Gene Expression Profiling

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United States of America Patent

APP PUB NO 20130260376A1
SERIAL NO

13813150

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Abstract

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The invention utilizes gene expression profiles in methods of predicting the likelihood that a patient's cancer will respond to standard-of-care therapy. Also provided are methods of identifying therapeutic agents that target cancer stem cells or epithelial cancers that have undergone an epithelial to mesenchymal transition using such gene expression profiles.

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Patent Owner(s)

Patent OwnerAddress
THE BROAD INSTITUTE INC415 MAIN STREET CAMBRIDGE MA 02142

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gupta, Piyush Boston, US 458 2640
Lander, Eric S Cambridge, US 79 1197
Mani, Sendurai Houston, US 6 64
Onder, Tamer T Cambridge, US 5 22
Weinberg, Robert Brookline, US 13 135

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