Enhanced antimicrobial lytic activity of a chimeric Ply187 endolysin

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United States of America Patent

PATENT NO 8790639
APP PUB NO 20130259849A1
SERIAL NO

13432758

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Abstract

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Peptidoglycan hydrolases are an effective new source of antimicrobials. A chimeric fusion protein of the Ply187 endopeptidase domain and LysK SH3b cell wall binding domain is a potent agent against Staphylococcus aureus in three functional assays.

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Patent Owner(s)

Patent OwnerAddress
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE1400 INDEPENDENCE AVENUE SW WASHINGTON DC 20250-1415

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Donovan, David M Baltimore, US 21 77
Mao, Jinzhe Crofton, US 1 2

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