Method and compositions for the treatment and detection of endothelin-1 related kidney diseases

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United States of America Patent

PATENT NO 10866249
APP PUB NO 20130252898A1
SERIAL NO

13906074

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present application relates to methods of treating HIV-associated nephropathy (HIVAN) and/or focal segmental glomerulosclerosis (FSGS) using endothelin-1 (ET-1) antagonists. The application further relates to a composition for the treatment of HIVAN and/or FSGS. A kit for detecting the presence of ET-1 or ET-1-associated biomarker in a biological sample is also disclosed.

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Patent Owner(s)

Patent OwnerAddress
MOREHOUSE SCHOOL OF MEDICINE720 WESTVIEW DRIVE SW ATLANTA GA 30310-1495

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Jacob-Mungin, Barbara A Atlanta, US 3 19
Newman, Gale W Duluth, US 20 38
Obialo, Chamberlain Atlanta, US 10 35

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