Methods Of Gene Amplification And Expression

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United States of America Patent

APP PUB NO 20130252327A1
SERIAL NO

13740694

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Abstract

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Disclosed are methods relating to amplification and expression of a nucleic acid sequence encoding a polypeptide of interest in recombinant cells, and cell lines and polypeptides produced from such methods. The methods disclosed herein permit the amplification of cell lines that express a polypeptide of interest in a relatively short period of time through the use of a bioreactor.

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Patent Owner(s)

Patent OwnerAddress
MEDAREX L L CROUTE 206 AND PROVINCE LINE ROAD PRINCETON NJ 08540

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Arunakumari, Alahari Pennington, US 16 216
Dai, Xiao-Ping Flemington, US 8 99
Ghebramariam, Haile Easton, US 2 2

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