IN VITRO METHOD FOR PREDICTING WHETHER A COMPOUND IS GENOTOXIC IN VIVO

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United States of America Patent

APP PUB NO 20130244896A1
SERIAL NO

13828655

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Abstract

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The invention is in the field of genomics and it provides an in vitro method for predicting whether a compound is genotoxic in vivo. It provides a method that employs the analysis of expression profiles of microRNAs in cells exposed to a potentially genotoxic compound. It was found that differential expression of a number of microRNAs could reliably predict whether a compound was a genotoxic or a non-genotoxic compound.

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Patent OwnerAddress
UNIVERSITEIT MAASTRICHTMINDERBROEDERSBERG 4-6 6211 LK MAASTRICHT
ACADEMISCH ZIEKENHUIS MAASTRICHTP DEBYELAAN 25 6229 HX MAASTRICHT

International Classification(s)

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  • 2013 Application Filing Year
  • C12Q Class
  • 2617 Applications Filed
  • 2019 Patents Issued To-Date
  • 77.15 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances2013201420152016201720182019202020212022202320240255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
LIZARRAGA-LOPEZ, Daneida JG Maastricht, NL 1 1
Rieswijk, Linda RP Maastricht, NL 1 1
Stephanus, Kleinjans Joseph Catharina AR Maastricht, NL 1 1
Van, Delft Joseph Henri Marie Etterbeek, BE 4 3

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  • 1 Citation Count
  • C12Q Class
  • 14.98 % this patent is cited more than
  • 12 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges22083518185511916147932901 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +050100150200250300350400450500550600650700750800850900

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