BERBERINE ALKALOID AS A MEDICAMENT FOR PREVENTION AND TREATMENT OF NEURAL DISEASE
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United States of America Patent
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Issued Date -
Sep 12, 2013
app pub date -
Mar 12, 2013
filing date -
Mar 12, 2012
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Abstract
The present invention is directed to method of preventing or treating neural disease or inhibiting accumulation of β-amyloid plaques in a subject by administering an effective dosage to the subject an agent (berberine) which inhibits the accumulation of β-amyloid- plaque, phospho-amyloid precursor protein (p-APP) and tau hyperphosphorylation in a mammalian brain.
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