Liver Sinusoid Model
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United States of America Patent
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Issued Date -
Sep 12, 2013
app pub date -
Mar 7, 2012
filing date -
Mar 7, 2012
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Abandoned
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Abstract
A liver sinusoid model includes a generally planar substrate having first and second generally parallel microchannels formed therein. A microporous membrane is disposed between and separating the first and second generally parallel microchannels. A first layer of cells lines one side of the membrane in the first microchannel. The first layer of cells are all a first common cell type. A second layer of cells extends parallel to the first layer of cells in one of the first microchannel and the second microchannel. The second layer of cells is all of a second common cell type. A liver sinusoid bioreactor utilizing the inventive model is also disclosed.
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