METHOD OF TREATMENT WITH BRAF INHIBITOR

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United States of America Patent

APP PUB NO 20130231347A1
SERIAL NO

13988116

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The disclosure is directed to a method of treating humans suffering from V600 mutant melanoma that incorporates the detection of the presence or absence of at least one mutation in at least one NRAS protein and/or at least one MEK1 protein, or a gene encoding said protein, and subsequently initiating treatment, modifying treatment, or discontinuing treatment with a chemo-therapeutic agent selected from a BRaf inhibitor or other suitable agent based upon the presence or absence of said mutation.

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Patent Owner(s)

Patent OwnerAddress
GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO 2) LIMITEDSTEVENAGE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bleam, Maureen Collegeville, US 2 2
Gilmer, Tona M Durham, US 19 164
Greger, James G Collegeville, US 3 46
Laquerre, Sylvie G King of Prussia, US 1 2
Liu, Li Collegeville, US 508 3582

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