BIPHASIC LIPID-VESICLE COMPOSITION AND METHOD FOR TREATING CERVICAL DYSPLASIA BY INTRAVAGINAL DELIVERY

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United States of America Patent

APP PUB NO 20130224283A1
SERIAL NO

13849455

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Abstract

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A biphasic lipid vesicle composition for treating cervical displasia by intravaginal delivery. The composition includes a suspension of lipid-bilayer vesicles having entrapped therein, an oil-in-water emulsion, human interferon alpha-2b and L-methionine, the composition having an interferon alpha-2b specific activity of between about 1-10 MIU (million international units) per gram composition, and between 0.01 to 0.5 weight percent L-methionine. In the treatment method, the composition is administered at a dose of between about 1-20 MIU interferon alpha-2b, and this dose is administered at least 3 days/week, for a period of at least 4 weeks.

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Patent Owner(s)

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HELIX BIOPHARMA CORPAURORA ONTARIO CANADA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
DOCHERTY, John M Richmond Hill, CA 3 12
FOLDVARI, Marianna Kitchener, CA 25 284
KUMAR, Praveen Saskatoon, CA 97 1147

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