METHOD FOR PREPARING MICROSPHERES AND MICROSPHERES PRODUCED THEREBY
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United States of America Patent
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app pub date -
Jan 18, 2013
filing date -
Jul 21, 2010
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Abstract
The present invention relates to a method for preparing microsphere and microspheres produced thereby. The method comprises: mixing a water-insoluble organic solvent with a dispersion solvent; mixing a polymer compound, a drug and a water-insoluble organic solvent to prepare a dispersed phase; mixing the dispersed phase with the dispersion solvent mixed with the water-insoluble organic solvent to prepare an emulsion; and adding a base or an acid to the prepared emulsion. With the method, it is possible to prepare a drug-containing polymeric microsphere cost-effectively and conveniently.
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