MODULAR DNA-BINDING DOMAINS AND METHODS OF USE
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United States of America Patent
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app pub date -
Jan 31, 2013
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Jan 12, 2009
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Abstract
The present invention refers to methods for selectively recognizing a base pair in a DNA sequence by a polypeptide, to modified polypeptides which specifically recognize one or more base pairs in a DNA sequence and, to DNA which is modified so that it can be specifically recognized by a polypeptide and to uses of the polypeptide and DNA in specific DNA targeting as well as to methods of modulating expression of target genes in a cell.
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