Chimeric Clotting Factors
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United States of America Patent
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Issued Date -
Aug 22, 2013
app pub date -
Jul 11, 2011
filing date -
Jul 9, 2010
priority date (Note) -
Abandoned
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Abstract
Chimeric clotting factors which localize the therapeutic to sites of coagulation (e.g., by being targeted to platelets or being activatable at sites of coagulation), have reduced clearance rates, have improved manufacturability, have reduced thrombogenicity, have enhanced activity, or have more than one of these characteristics are described as are methods for making chimeric clotting factors and methods for improving hemostasia using these clotting factors.
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