HYPEROSMOTIC PREPARATIONS COMPRISING 5-AMINOLEVULINIC ACID OR DERIVATIVE AS PHOTOSENSITIZING AGENT

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United States of America Patent

APP PUB NO 20130211215A1
SERIAL NO

13806578

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Abstract

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Provided herein are improved methods of photodynamic treatment and diagnosis of cancer and non-cancerous conditions in the gastrointestinal tract, e.g. in the colon, and in particular hyperosmotic enema preparations for use in such methods. The enema preparations comprise a photosensitizer which is 5-aminolevulinic acid (5-ALA) or a precursor or derivative thereof, e.g. a 5-ALA ester, in combination with at least one hyperosmotic agent. The methods and preparations herein described are particularly suitable for use in photodynamic methods of treating and/or diagnosing colorectal cancer.

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Patent Owner(s)

Patent OwnerAddress
PHOTOCURE ASA0275 OSLO

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Godal, Aslak Oslo, NO 28 400
Heglund, Inger Ferner Nesoya, NO 1 3
Klaveness, Jo Oslo, NO 187 4245

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