PROCESS FOR THE PREPARATION OF 17-DESOXY-CORTICOSTEROIDS
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United States of America Patent
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Issued Date -
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app pub date -
Jul 20, 2011
filing date -
Jul 20, 2010
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The present invention provides an improved process for the preparation of 17-desoxy corticosteroid derivatives in a single chemical step by reacting the 17-hydroxy starting material with an excess of Trimethylsilyl Iodide. The present invention is specifically advantageous in preparing 17-desoxy corticosteroid derivatives having one or more halogen groups at positions 2, 6, 7 or 9 of the corticosteroid such as Clocortolone of Desoximetasone.
First Claim
all claims..Other Claims data not available
Family
Country | kind | publication No. | Filing Date | Type | Sub-Type |
---|---|---|---|---|---|
CA | A1 | CA2805832 | Jul 20, 2011 | Patent | Application |
Type : Patent Sub-Type : Application | |||||
APPLICATION LAID OPEN | PROCESS FOR THE PREPARATION OF 17-DESOXY-CORTICOSTEROIDS | Jan 26, 2012 | |||
WO | A1 | WO2012011106 | Jul 20, 2011 | Patent | Application |
Type : Patent Sub-Type : Application | |||||
INTERNATIONAL APPLICATION PUBLISHED WITH INTERNATIONAL SEARCH REPORT | PROCESS FOR THE PREPARATION OF 17-DESOXY-CORTICOSTEROIDS | Jan 26, 2012 | |||
EP | B1 | EP2596007 | Jul 20, 2011 | Patent | Grant |
Type : Patent Sub-Type : Grant | |||||
Patent | PROCESS FOR THE PREPARATION OF 17-DESOXY-CORTICOSTEROIDS | Jan 06, 2016 | |||
IL | A | IL224325 | Jan 20, 2013 | Patent | Application |
Type : Patent Sub-Type : Application | |||||
Patent Application | Processes for preparation of 11-(oxo/ß-hydroxy)-16-methyl-21-hydroxy-pregna-1,4-diene-3,20-dione derivatives | May 31, 2016 | |||
US | B2 | US10112970 | Jan 09, 2017 | Patent | Grant |
Type : Patent Sub-Type : Grant | |||||
GRANTED PATENT AS SECOND PUBLICATION | Process for the preparation of 17-desoxy-corticosteroids | Oct 30, 2018 |
- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | |
---|---|---|
TARO PHARMACEUTICALS INDUSTRIES LTD | 14 HAKITOR STREET HAIFA BAY HAIFA 2624761 |
International Classification(s)

- 2011 Application Filing Year
- C07J Class
- 100 Applications Filed
- 57 Patents Issued To-Date
- 57 % Issued To-Date
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
---|---|---|---|
Cherniak, Simon | Haifa, IL | 3 | 0 |
# of filed Patents : 3 Total Citations : 0 | |||
Cyjon, Rosa | Haifa, IL | 10 | 27 |
# of filed Patents : 10 Total Citations : 27 | |||
Nudelman, Igor | Haifa, IL | 11 | 44 |
# of filed Patents : 11 Total Citations : 44 | |||
Ozer, Ilana | Yokneam llit, IL | 5 | 0 |
# of filed Patents : 5 Total Citations : 0 |
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Patent Citation Ranking
- 0 Citation Count
- C07J Class
- 0 % this patent is cited more than
- 12 Age
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Maintenance Fees
Fee | Large entity fee | small entity fee | micro entity fee | due date |
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Fee | Large entity fee | small entity fee | micro entity fee |
---|---|---|---|
Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |
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