Aqueous Pharmaceutical Composition With Enhanced Stability
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United States of America Patent
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Issued Date -
Aug 15, 2013
app pub date -
Feb 8, 2013
filing date -
Feb 10, 2012
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Abandoned
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Abstract
The present invention is an aqueous pharmaceutical composition that includes an ionized therapeutic agent, an ionic component and guar gum. The guar gum is present in the composition a concentration sufficient to limit interactions between the ionized therapeutic agent and the ionic component thereby imparting stability to the composition. The composition is preferably at or near physiologic pH. The aqueous pharmaceutical composition has been found particularly useful as an aqueous ophthalmic, otic or nasal composition. The pharmaceutical composition, due to its characteristics, is particularly suitable as an ophthalmic composition.
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