USING A NOVEL HIGH-THROUGHPUT YEAST CELL-BASED SCREENING PLATFORM TO IDENTIFY HMG-COA REDUCTASE INHIBITORS FROM NATURAL PRODUCTS AND THE USES OF SUCH INHIBITORS THEREOF
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United States of America Patent
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Issued Date -
Aug 15, 2013
app pub date -
Feb 8, 2013
filing date -
Feb 9, 2012
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Abandoned
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Abstract
Methods of screening, identifying and isolating HMG-CoAR inhibitors are disclosed herein. In particular, said method is useful for screening natural raw products. The present invention also provides potent HMG-CoAR inhibitors for treatment and prevention of diseases and conditions associated with elevated cholesterol and/or blood lipid levels.
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